Extracellular Matrix Organization, Structure, and Function
نویسندگان
چکیده
Heart valves are thin, complex, layered connective tissues that direct blood flow in one di‐ rection through the heart. There are four valves in the heart, located at the entrance to and exit from the ventricular chambers. The normal function of the heart valves is essential to cardiovascular and cardiopulmonary physiology. The opening and closing of valve leaflets at precise times during the cardiac cycles contributes to the generation of sufficiently high pressure to eject blood from the ventricles, and also prevents blood from flowing backwards into the heart instead of forward towards the systemic circulation and the lungs.
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